Abstract
Recently, a region encompassing the promoter and intron 1 of the paraoxonase 1 gene (PON1) have been associated with the risk of developing Alzheimer's disease (AD) in a large pan-ethnic (Caucasian and African-American) dataset. We attempted to replicate this observation in a large French study of sporadic cases and controls. We confirmed that the proximal promoter and 5′ sequence of the PON1 gene may harbor unknown functional variant(s) associated with the risk of developing AD. © 2007.
Author supplied keywords
Cite
CITATION STYLE
Chapuis, J., Boscher, M., Bensemain, F., Cottel, D., Amouyel, P., & Lambert, J. C. (2009). Association study of the paraoxonase 1 gene with the risk of developing Alzheimer’s disease. Neurobiology of Aging, 30(1), 152–156. https://doi.org/10.1016/j.neurobiolaging.2007.05.021
Register to see more suggestions
Mendeley helps you to discover research relevant for your work.
