Objective Asymptomatic vaginal colonization with Candida species is a known risk factor for vulvovaginal candidiasis (VVC). Taking known risk factors for symptomatic VVC, the authors sought to identify factors associated with asymptomatic colonization. Study design As part of a randomized controlled trial which compared vaginal candidal colony counts in women taking garlic tablets or placebo, 192 asymptomatic women collected a baseline screening swab for Candida species. Eligibility for this study included at least one self-reported episode of VVC in the previous 12 months and age 18-50 years. Known risk factors for VVC were compared in women colonized with candida and those without colonization. Results 37% of asymptomatic women who self-reported VVC in the previous 12 months were colonized with vaginal Candida species. Using multivariate analysis, two factors were associated with asymptomatic colonization: a current sexual partner (P = 0.02) and being born outside of Australia (P = 0.05). Use of oral contraceptives was not statistically significant (P = 0.27). Conclusions Clinical relevance of asymptomatic colonization with vaginal yeast and its link to episodes of VVC warrants further investigation. © 2013 Elsevier Ireland Ltd. All rights reserved.
CITATION STYLE
Watson, C. J., Fairley, C. K., Grando, D., Garland, S. M., Myers, S. P., & Pirotta, M. (2013). Associations with asymptomatic colonization with candida in women reporting past vaginal candidiasis: An observational study. European Journal of Obstetrics and Gynecology and Reproductive Biology, 169(2), 376–379. https://doi.org/10.1016/j.ejogrb.2013.03.030
Mendeley helps you to discover research relevant for your work.