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C-26 and C-30 apocarotenoids from seeds of Ditaxis heterantha with antioxidant activity and protection against DNA oxidative damage.

by María D Méndez-Robles, Herry H Permady, María E Jaramillo-Flores, Eugenia C Lugo-Cervantes, Anaberta Cardador-Martínez, Alejandro A Canales-Aguirre, Fernando López-Dellamary, Carlos M Cerda-García-Rojas, Joaquín Tamariz show all authors
Journal of Natural Products (2006)

Abstract

The hexane extracts of seeds of Ditaxis heterantha afforded two new apocarotenoids whose structures corresponded to methyl 3-oxo-12'-apo-epsilon-caroten-12'-oate (1) (heteranthin) and methyl 3beta,6beta-epoxy-5beta-hydroxy-4,5-dihydro-8'-apo-epsilon-caroten-8'-oate (2) (ditaxin). Both compounds were evaluated for antioxidant activity and protection against DNA oxidative damage by using DPPH free radical scavenging and Comet assays, respectively.

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