Nervous system development requires the specification of numerous neural stem cells. Subsequently these stem cells divide in a spatially and temporally controlled manner to generate the diverse cell types found in the different layers of the nervous system. Lineage specification is brought about by transcriptional regulators, which often act as transcriptional repressors.
CITATION STYLE
Edenfeld, G., Pielage, J., & Klämbt, C. (2002, August 1). Cell lineage specification in the nervous system. Current Opinion in Genetics and Development. Elsevier Ltd. https://doi.org/10.1016/S0959-437X(02)00328-3
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