Chemical composition, Aedes mosquito larvicidal activity, and repellent activity against Triatoma rubrofasciata of Severinia monophylla leaf essential oil

Abstract

Aedes aegypti and Ae. albopictus are key vectors in the spread of arboviruses such as dengue, chikungunya, yellow fever, and Zika. Triatoma rubrofasciata is an “assassin bug” whose populations and association with humans have dramatically increased and may represent a serious health concern. Control of insect vectors is a logical course of action to prevent the spread of these insect-borne infections. This work presents the leaf essential oil composition, mosquito larvicidal activities, and insect-repellent activity of Severinia monophylla. The essential oil of S. monophylla from Vietnam was obtained by hydrodistillation and analyzed by gas chromatography and mass spectrometry. The major components were sabinene, β-caryophyllene, bicyclogermacrene, germacrene D, (E)-nerolidol, globulol, and linalool. The leaf essential oil showed remarkable larvicidal activity against Ae. aegypti with LC 50 (48 h) of 7.1 μg/mL and Ae. albopictus with LC 50 (48 h) of 36 μg/mL. The essential oil also showed repellent activity on T. rubrofasciata at a concentration of 0.5%.