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Chemical constituents from leaves of Boehmeria nivea

by Chuang Liu, Kun Zou, Zhiyong Guo, Yuying Zhao, Fan Cheng, Hongqi Zhang
Zhongguo Zhong yao za zhi Zhongguo zhongyao zazhi China journal of Chinese materia medica (2010)

Abstract

OBJECTIVE: To study the chemical constituents from the leaves of Boehmeria nivea. METHOD: The leaves were extracted by 95% EtOH at room temprature, the chemical leaves were isolated and purified by repeated silica gel column chromatography, Sephadex LH-20 column chromatography and semipreparative HPLC, and their structures were identified by physical and chemical properties and spectroscpoic methods. RESULT: One compound isolated from n-butanol fraction, four compounds were obtained from ethyl acetate fraction and three compounds from petroleum ether fraction. Their structures were elucidated as kiwiionoside (1), eugenyl beta-rutinoside (2), uracil (3), beta-sitosterol glucoside (4), 3-hydroxy-4-methoxy-benzoic acid (5), cholesterol (6), alpha-amyrin (7). nonacosanol (8). CONCLUSION: Compounds 1-3, 5-8 were isolated from the genus Boehmeria for the first time.

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