A common polymorphism is associated with body mass index in Uyghur population

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Abstract

We aimed at observing the association of a common genetic variant near the INSIG2 gene (rs7655505) with body mass index (BMI) related obesity in a population-based association study in Uyghur population. We observed a significant association of rs7566605 polymorphism with BMI related obesity in Uyghurs with an odds ratio of 1.47 (95% CI 1.11-1.95, P = 0.006) under a dominant model (CC + GC versus GG). The mean BMI of rs7566605 CC + GC was 0.59 kg/m2 higher than for GG genotype (P = 0.024), regardless of sex and age. © 2008 Elsevier Ireland Ltd. All rights reserved.

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Zhang, J., Lin, R., Wang, F., Lu, M., Lin, R. yong, Wang, S. zhen, … Wang, X. feng. (2008). A common polymorphism is associated with body mass index in Uyghur population. Diabetes Research and Clinical Practice, 81(2). https://doi.org/10.1016/j.diabres.2008.03.022

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