Cross Protection Against Taenia Taeniaeformis in Rats Vaccinated with Non-Viable Oncospheres of Asian Taenia or T. Saginata

Abstract

It was determined to examine whether rats injected with non-viable onco-spheres of Asian Taenia or Taenia saginata became resistant to challenge infection with eggs of Taenia taeniaeformis, since (a) metacestodes of Asian Taenia and T. taeniaeformis develop in the liver of pigs and rats, respectively, and (b) Asian Taenia and T. saginata have human origins. Rats injected intravenously or subcutaneously with complete Freund's adjuvant with non-viable oncospheres of Asian Taenia showed statistically significant resistance to challenge infection with eggs of T taeniaeformis, whereas those injected with non-viable oncospheres of T. saginata did not show any resistance. © 1994, Cambridge University Press. All rights reserved.