The effect of 50 Hz electromagnetic fields on the immune system was assessed by measuring the cytokine production of the peripheral blood mononuclear cells, (h-PBMCs) of a healthy individual. The h-PBMCs were exposed in vitro to varying magnetic flux densities of 1, 3, 10, and 30 milliTesla for 3 days. Changes in cytokine production of IL-1β, IL-2, IL-6, IL-10, IFN-γ, and TNF-α were studied using the ELISA method. Significant reduction in TNFα production by the EMF-exposed h-PBMCs, in comparison with the non-exposed cells, was detected at all exposure levels (p < 0.05, p < 0.01). Significant increase in IL-1β production and decreased in IFN-γ production were also detected at some exposure strength. No significant differences were detected between the control and the EMF-exposed cells in the production of the other cytokines.
CITATION STYLE
Jonai, H., Villanueva, M. B. G., & Yasuda, A. (1996). Cytokine profile of human peripheral blood mononuclear cells exposed to 50 Hz EMF. Industrial Health, 34(4), 359–368. https://doi.org/10.2486/indhealth.34.359
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