Data Integration Solution for Organ-Specific Studies: An Application for Oral Biology

Abstract

The human oral cavity is a complex ecosystem where multiple interactions occur and whose comprehension is critical in understanding several disease mechanisms. In order to comprehend the composition of the oral cavity at a molecular level, it is necessary to compile and integrate the biological information resulting from specific techniques, especially from proteomic studies of saliva. The objective of this work was to compile and curate a specific group of proteins related to the oral cavity, providing a tool to conduct further studies of the salivary proteome. In this paper we present a platform that integrates in a single endpoint all available information for proteins associated with the oral cavity. The proposed tool allows researchers in biomedical sciences to explore microorganisms, proteins and diseases, constituting a unique tool to analyse meaningful interactions for oral health. © Springer-Verlag Berlin Heidelberg 2013.