Developmental control of growth and cell cycle progression in Drosophila.

Abstract

Drosophila melanogaster provides an outstanding experimental system to study the regulation of cell cycle progression during animal development. Sophisticated forward and reverse genetic techniques and the ability to observe detailed cell biological phenomena in vivo have allowed an unparalleled analysis of the cell cycle in the context of a whole animal. This chapter provides an overview of the diverse modes of cell cycle control that are utilized at different stages of Drosophila development.