Hypermethylation of CpG islands in gene promoter regions has been shown to be a predictive biomarker for certain diseases. Most current methods for methylation profiling are not well-suited for clinical analysis. Here, we report the development of an inexpensive device and an epigenotyping assay with a format conducive to multiplexed analysis. © 2014 the Partner Organisations.
CITATION STYLE
Heimer, B. W., Shatova, T. A., Lee, J. K., Kaastrup, K., & Sikes, H. D. (2014). Evaluating the sensitivity of hybridization-based epigenotyping using a methyl binding domain protein. Analyst, 139(15), 3695–3701. https://doi.org/10.1039/c4an00667d
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