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Journal Article

Evaluation of IL18 and IL18R1 polymorphisms: Genetic susceptibility to knee osteoarthritis

International Journal of Immunogenetics (2012) 39(2) 106-109
DOI: 10.1111/j.1744-313X.2011.01060.x
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Abstract

We examined single-nucleotide polymorphisms (SNPs) in IL18 and IL18/R1 genes and knee OA. IL18 rs1946518 wild-type allele was more frequently observed in cases (P=0.04). Haplotype 1 was more frequently observed in cases (P=0.04). Genetic variation in the promoter region of IL18, but not IL18R1, may be associated with OA. © 2011 Blackwell Publishing Ltd.

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Hulin-Curtis, S. L., Bidwell, J. L., & Perry, M. J. (2012). Evaluation of IL18 and IL18R1 polymorphisms: Genetic susceptibility to knee osteoarthritis. International Journal of Immunogenetics, 39(2), 106–109. https://doi.org/10.1111/j.1744-313X.2011.01060.x

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