Here we describe an ultra-low-cost origami-based approach for large-scale manufacturing of microscopes, specifically demonstrating brightfield, darkfield, and fluorescence microscopes. Merging principles of optical design with origami enables high-volume fabrication of microscopes from 2D media. Flexure mechanisms created via folding enable a flat compact design. Structural loops in folded paper provide kinematic constraints as a means for passive self-alignment. This light, rugged instrument can survive harsh field conditions while providing a diversity of imaging capabilities, thus serving wide-ranging applications for cost-effective, portable microscopes in science and education. © 2014 Cybulski et al.
CITATION STYLE
Cybulski, J. S., Clements, J., & Prakash, M. (2014). Foldscope: Origami-based paper microscope. PLoS ONE, 9(6). https://doi.org/10.1371/journal.pone.0098781
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