Late-onset Alzheimer's disease (LOAD) is an age related neurodegenerative disease with a high prevalence that places major demands on healthcare resources in societies with increasingly aged populations. The only extensively replicable genetic risk factor for LOAD is the apolipoprotein E gene. In order to identify additional genetic risk loci we have conducted a genome-wide association (GWA) study in a large LOAD case - control sample, reducing costs through the use of DNA pooling.
CITATION STYLE
Abraham, R., Moskvina, V., Sims, R., Hollingworth, P., Morgan, A., Georgieva, L., … Kirov, G. (2008). A genome-wide association study for late-onset Alzheimer’s disease using DNA pooling. BMC Medical Genomics, 1(1). https://doi.org/10.1186/1755-8794-1-44
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