Immune Signaling in Neurodegeneration

Abstract

Stevens and colleagues explore the growing evidence of immune involvement in the initiation and progression of neurodegenerative disease. The authors examine how immune pathways identified by GWASs and histopathological studies contribute to aberrant cellular responses, pathological protein aggregation, and neural deterioration in Alzheimer's Disease, Parkinson's Disease, and other age-related neurodegenerative diseases.