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Impact of young age on treatment efficacy and safety in advanced colorectal cancer: a pooled analysis of patients from nine first-line phase III chemotherapy trials.

by Charles D Blanke, Brian M Bot, David M Thomas, Archie Bleyer, Claus-Henning Kohne, Matthew T Seymour, Aimery De Gramont, Richard M Goldberg, Daniel J Sargent show all authors
Journal of Clinical Oncology ()

Abstract

Colorectal cancer predominantly occurs in the elderly, but approximately 5% of patients are 50 years old or younger. We sought to determine whether young age is prognostic, or whether it influences efficacy/toxicity of chemotherapy, in patients with advanced disease.

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