THE INFLUENCE OF NUTRITIONAL STATUS ON THE PROGNOSIS OF PATIENTS RECEIVING TREATMENT WITH HEMODIALYSIS

Abstract

BACKGROUND. To assess the effect of duration of hemodialysis therapy on the body composition of patients with chronic kidney disease stage 5. To study the cumulative survival of patients receiving chronic hemodialysis therapy, depending on changes in their body composition and nutritional status. PATIENTS AND METHODS. 84 patients with terminal kidney disease from one hemodialysis center were observed for two years. Diamant-AIST device was used for the evaluation of the compartments’ volumes and nutritional status. RESULTS. Negative correlations between the time on the hemodialysis treatment and studied bioelectrical impedance analysis parameters were observed: correlation with total fluid volume (r=-0,6, p<0,05), fat free mass (r=-0,558, p<0,05), free water volume (r=-0,588, p<0,05), fat mass (r=-0,458, p<0,05), lean body mass (r=-0,564, p<0,05), active cell mass (r=-0,5, p<0,05). There was a statistically significant difference between the cumulative survival with regard to mortality from all causes and cardiovascular events of the patients with high and low values of the fat body mass. CONCLUSIONS. Our study showed that change in the compartment’s volumes is associated with the length of hemodialysis treatment. There is a statistically significant difference in survival of patients with low and high free fat mass.