No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression

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Abstract

In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations. © 2010 Elsevier Ltd.

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Serretti, A., Chiesa, A., Calati, R., Massat, I., Linotte, S., Kasper, S., … Mendlewicz, J. (2011). No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression. Psychiatry Research, 188(1), 166–169. https://doi.org/10.1016/j.psychres.2010.11.023

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