The sequence of the human genome has dramatically accelerated biomedical research. Here I explore its impact, in the decade since its publication, on our understanding of the biological functions encoded in the genome, on the biological basis of inherited diseases and cancer, and on the evolution and history of the human species. I also discuss the road ahead in fulfilling the promise of genomics for medicine.
E S Lander, International Human Genome Sequencing Consortium, L M Linton, B Birren, C Nusbaum, M C Zody, et al. in Nature (2001)
E S Lander, A Heaford, A Sheridan, L M Linton, B Birren, A Subramanian, et al. in Nature (2001)
M Frazier, R A Gibbs, D M Muzny, S E Scherer, J B Bouck, E J Sodergren, et al. in Nature (2001)Save reference to library 2 readers
International Human Genome Consortium in Nature (2001)Save reference to library 5 readers
Chen YJ; International Human Genome Sequencing Consortium. Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, Kann L, Lehoczky J, LeVine R, McEwan P, McKernan K, Meldrim J, Mesirov JP, Miranda C, Morris W, Naylor J in Nature (2001)
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