Sign up & Download
Sign in

Interrelationships of transcriptional machinery with nuclear architecture.

by G S Stein, A J van Wijnen, J L Stein, J B Lian
Critical reviews in eukaryotic gene expression ()

Abstract

There is increasing evidence for functional linkages between nuclear architecture and the regulation of gene expression. The nuclear matrix provides a paradigm for involvement of nuclear morphology in assembly of the biochemical machinery for physiological control of transcription. Mechanisms are being experimentally defined that direct regulatory factors to subnuclear sites that support gene expression. Consequently, we are gaining insight into the rules that govern transcriptional control within the three-dimensional context of nuclear organization.

Cite this document (BETA)

Readership Statistics

1 Reader on Mendeley
by Discipline
 
by Academic Status
 
100% Other Professional

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Already have an account? Sign in