The investigation of linkage between a quantitative trait and a marker locus

Abstract

Procedures are given, using sib pairs, for estimating linkage between a known m-allele locus and a hypothesized two-allele locus that governs a quantitative trait. Random mating and linkage equilibrium are assumed. Also given are parametric and nonparametric methods for detecting linkage when the trait in question is governed by several two-allele loci, provided there is no epistasis. © 1972 Plenum Publishing Corporation.