Misoprostol is a synthetic prostaglandin that can be given orally or vaginally. In most countries misoprostol has not been licensed for use in pregnancy, but its unlicensed use is common because misoprostol is cheap, stable at room temperature and effective in causing uterine contractions. Oral use of misoprostol may be convenient, but high doses could cause uterine hyperstimulation and uterine rupture which may be life-threatening for both mother and fetus.
CITATION STYLE
Alfirevic, Z., & Weeks, A. (2014). Oral misoprostol for induction of labour. Cochrane Database of Systematic Reviews. The Cochrane Library, (6), Art. No. CD001338.
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