Panretinal Photocoagulation (PRP)

Abstract

Panretinal photocoagulation (PRP) uses light energy to create thermal injury to the retinal tissue. When PRP is applied to areas of poorly perfused retina, pathologic levels of vascular endothelial growth factor (VEGF) are suppressed. PRP is an effective method of treating ischemic retinal vascular disease such as proliferative diabetic retinopathy (PDR). Fluorescein angiography should be performed to identify areas of neovascularization and retinal ischemia to guide application of PRP. A clear view of the fundus facilitates delivery of PRP. Effective delivery of PRP may be limited or delayed if the ocular media is obscured by corneal edema, cataract, and/or vitreous hemorrhage.