Parent of origin effect and differential allelic expression of BDNF Val66Met in suicidal behaviour.
The world journal of biological psychiatry the official journal of the World Federation of Societies of Biological Psychiatry (2011)
- PubMed: 20726824
Available from www.ncbi.nlm.nih.gov
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Abstract
Brain-derived neurotrophic factor (BDNF) plays an important role in the pathophysiology of mood disorders and may also be involved in suicidal behaviour since BDNF levels are decreased in brain and plasma of suicide victims. Because the differential allelic expression of Val66Met BDNF gene on suicidal behaviour has not been investigated, we analyzed the parent-of-origin effect (POE) in suicide attempters and the differential expression of BDNF Val66Met alleles in suicide victims.
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