Progress on Supramolecular Structure of Inclusion Compounds of Cyclodextrins and their Derivatives

Abstract

Cyclodextrins (CDs) are cyclic oligosaccharides consisting of six or more D-glucose units. One of most prominent properties of these compounds is the formation of inclusion compounds with a variety of guest molecules. Since the first success in 1965 for the structure determination of the α-cyclodextrin inclusion compound with potassium acetate, structures of more than 100 crystalline inclusion compounds have been reported. X-ray crystallography has been a major source of information about the three-dimensional structure of the host-guest interactions. In this paper a review is presented on the advancement of supramolecular structure of inclusion compounds for cyclodextrins and their derivatives.