Objectives: Bordetella pertussis is the etiological agent of whooping cough, a bacterial infection of especially children, which may be fatal without treatment. In frame of studies to investigate putative effects of vaccination on host-pathogen interaction and clonal distribution of strains, in addition to Corynebacterium diphtheriae and Clostridium tetani toxoid vaccines, also whole-cell and acellular pertussis vaccines were analyzed by mass spectrometry. Data description: LC-MS/MS spectra were generated and analyzed using B. pertussis genome data and proteins present in whole-cell and acellular pertussis vaccines were identified. Subcellular localization of proteins and presence of signal peptides was determined bioinformatically.
CITATION STYLE
Möller, J., Kraner, M. E., & Burkovski, A. (2019). Proteomics of Bordetella pertussis whole-cell and acellular vaccines. BMC Research Notes, 12(1). https://doi.org/10.1186/s13104-019-4373-2
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