Pilocarpine 4% gel and pilocarpine 4% solution were compared in young normal subjects for their effects on induced myopia. The pilocarpine 4% solution produced marked myopia lasting one to two hours which indicates that a qid therapeutic regimen produces about three to six hours of blurred vision during waking hours. The gel-induced myopic effects returned to normal in most subjects nine hours after a single instillation. Thus, pilocarpine-gel-induced myopic effects occur principally while asleep and are reduced substantially upon awakening. This allows patients to carry on normal activities throughout the day.
CITATION STYLE
Mandell, A. I., Bruce, L. A., & Khalifa, M. A. (1988). Reduced cyclic myopia with pilocarpine gel. Annals of Ophthalmology, 20(4), 133–135.
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