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Refinement of the fluid-mosaic model of membrane structure.

by J N Israelachvili
Biochimica et biophysica acta ()

Abstract

Certain molecular packing criteria previously employed in a quantitative analysis of lipid micelles and bilayers are here extended to biological membranes. The inclusion of both thermodynamic and packing considerations point to a highly complex self-assembly mechanism in which the organization of lipids and proteins is highly coupled, with far reaching consequences as regards the structure and function of biological membranes.

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