Gene polymorphisms of the renin-angiotensin system are involved in the pathophysiology of hypertension. We genotyped 4 polymorphisms of angiotensinogen (AGT) gene A-20C (rs5050), A-6G (rs5051), C3889T (rs4762), and C4072T (rs699) by polymerase chain reaction-restriction fragment length polymorphism in 652 patients and 780 controls to examine the association of AGT and hypertension in a Northern Han Chinese population. There were significant differences in the distribution of genotypes and allele frequencies at C4072T between the patients and the controls (both P
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HongMei, L., ZhiRong, D., Lin, Z., Tong, W., ZhiHui, D., JingPing, L., … ChangChun, Q. (2014). The relationship between angiotensinogen gene polymorphisms and essential hypertension in a Northern Han Chinese population. Angiology, 65(7), 614–619. Retrieved from http://proxy.lib.umich.edu/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=lhh&AN=20143281025&site=ehost-live&scope=site http://ang.sagepub.com/content/by/year email: changchun_qiu@163.com
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