Results of the First International Granulocyte Serology Workshop

Abstract

Eleven laboratories paticipated in the First International Workshop of Granulocyte Serology. Participants were asked to identify any granulocyte‐reactive antibodies present in 12 human sera distributed as unknown samples. Granulocyte immunofluorescence and granulocyte micro‐agglutination were the most commonly used techniques. The incidence of false‐positive and false‐negative reactions was 15 and 4%, respectively. Most laboratories were able to distinguish between granulocyte‐specific and anti‐HLA antibodies using platelet absorption. The identification of the specificity of granulocyte‐specific antibodies caused the most problems; these were correctly identified on only 57% of occasions. © 1990 S. Karger AG, Basel