Uterine rupture is a serious and often tragic complication that is life threatening to both mother and child. It occurs at a frequency of around 1% in patients with a previously scarred uterus. Rupture of an unscarred uterus is an unexpected and devastating complication of pregnancy. With the increased use of misoprostol as a labor-inducing agent, cases of rupture of an unscarred uterus following its use have been published in the literature. We report a case of uterine rupture in a multigravid woman with an intrauterine fetal death at 29 weeks' gestation whose labor was induced with misoprostol. A review of all cases of uterine rupture with misoprostol induction is also included. Excessive doses of misoprostol should be used with extreme caution in multiparous women and in patients with a previously scarred uterus even in the context of intrauterine fetal death or termination of pregnancy.
CITATION STYLE
Khabbaz, A. Y., Usta, I. M., El-Hajj, M. I., Abu-Musa, A., Seoud, M., & Nassar, A. H. (2001). Rupture of an unscarred uterus with misoprostol induction: Case report and review of the literature. Journal of Maternal-Fetal Medicine, 10(2), 141–145. https://doi.org/10.1080/jmf.10.2.141.145-8
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