Saponins from the rhizomes of Anemarrhena asphodeloides Bge

Abstract

ABSTRACT AIM: To investigate the constituents of the rhizomes of Anemarrhena asphodeloides Bge. and look for new active compounds. METHODS: Compounds were isolated with porous resin, silica gel, HPLC and so on, and identified by chemical and spectroscopic evidence. RESULTS: Two steroidal saponins were obtained, and their structures were shown to be (5β, 25S)-spirostan-3β, 15α, 23α-triol-3-O-β-D-glucopyranosyl (1→2)-β-D-galactopyranoside (1) and (5β, 25S)-spirostan-3β, 23α-diol-3-O-β-D-glucopyranosyl(1→2)-β-D-galactopyranoside (2). CONCLUSION: They were new compounds, named as timosaponin-F (1) and timosaponin-G (2), respectively.