The stochastic evolution of a protocell. The Gillespie algorithm in a dynamically varying volume
Computational and Mathematical Methods in Medicine (2011)
- ISSN: 1748670X
- DOI: 10.1155/2012/423627
- arXiv: 1112.1281
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Alessandro Filisetti's profile on Mendeley.
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Abstract
In the present paper we propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some specific molecules, belonging to the reactions set. This allows us to study the stochastic evolution of a protocell, whose volume increases because of the production of container molecules. Several protocells models are considered and compared with the deterministic models.
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