The iron(II)-catalyzed domino isomerization of 3-alkyl/aryl-4-arylisoxazoles provides a selective access to a wide range of structurally diverse highly substituted indole-3-carboxylates. The operational simplicity, high atom efficiency, and the use of stable starting materials and an inexpensive and low-toxicity catalyst are some of the attractive features of this tandem double ring-opening-ring-closure strategy.
CITATION STYLE
Bodunov, V. A., Galenko, E. E., Galenko, A. V., Novikov, M. S., & Khlebnikov, A. F. (2018). Synthesis of Substituted Indole-3-carboxylates by Iron(II)-Catalyzed Domino Isomerization of 3-Alkyl/aryl-4-aryl-5-methoxyisoxazoles. Synthesis (Germany), 50(14), 2784–2798. https://doi.org/10.1055/s-0036-1591576
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