Sign up & Download
Sign in

Tyrosine and its potential use as a countermeasure to performance decrement in military sustained operations.

by J O Owasoyo, D F Neri, J G Lamberth
Aviation, space, and environmental medicine ()

Abstract

We review the biochemistry and physiological role of the amino acid tyrosine in normal and stressful situations such as military sustained operations. Sustained operations consist of continuous work periods exceeding 12 h and often involve sleep loss and fatigue. These, in turn, can lead to stress, anxiety, mood deterioration, and performance decrement. Experimental data in the literature suggest that tyrosine, a precursor of the neurotransmitter norepinephrine, may be useful in counteracting any stress-related performance decrement and mood deterioration in the following way. First, various forms of stress induce brain depletion of catecholamines, especially norepinephrine, in animals. Second, brain norepinephrine levels are closely related to stress-induced performance decrement in animals. Third, the administration of tyrosine may minimize or reverse stress-induced performance decrement by increasing depleted brain norepinephrine levels. The types of performance degradation expected in military sustained operations and the potential physiological role tyrosine might play in improving mood and performance are discussed.

Cite this document (BETA)

Readership Statistics

4 Readers on Mendeley
by Discipline
 
 
by Academic Status
 
50% Ph.D. Student
 
25% Student (Bachelor)
 
25% Researcher (at a non-Academic Institution)

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Already have an account? Sign in