Within-person variability in urinary bisphenol A concentrations: measurements from specimens after long-term frozen storage.
- ISSN: 10960953
- DOI: 10.1016/j.envres.2009.04.004
- PubMed: 19463991
Abstract
Bisphenol A (BPA) is an estrogenic contaminant of food and water associated with adverse developmental effects in laboratory animals. BPA has recently been linked to morbidity in adult humans, but studies of developmental effects in humans are methodologically more difficult. The ability to measure BPA in urine samples after long-term storage could aid in such studies. Because the half-life of BPA is < 6h, a single measurement would be useful only if the environmental exposure is relatively constant over weeks or months. Our aims were to evaluate the stability of BPA in specimens after 22-24 years of storage and to measure within-person temporal variability in urinary BPA.
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