Postdoc Position - Department of Clinical chemistry, microbiology and immunology

Location
Gent, Belgium
Salary
Competitive
Posted
Nov 08, 2017
Closes
Dec 20, 2017
Ref
106419
Contract Type
Full Time
Job Type
Postdoc
Last application date Jan 31, 2018 16:04
Department GE06 - Department of Clinical chemistry, microbiology and immunology
Contract Limited duration
Degree PhD
Occupancy rate 100%
Vacancy Type Research staff
Job description
The research group of Prof. Tom Taghon, located in Ghent, Belgium, is looking for a talented and highly motivated postdoctoral researcher to join our team. Research in our lab is focused on the functional characterization of the molecular mechanisms that control the early stages of T cell development in human (Van de Walle et al., Journal of Experimental Medicine 2013; Van de Walle et al., Nature Communications 2016). Using human primary hematopoietic stem cells and thymocytes, successful candidates will apply state-of-the-art molecular and cell culture approaches to improve our understanding of the stepwise conversion of hematopoietic precursor cells into human TCRαβ and TCRγδ T cells. Techniques include single cell RNAseq, ChIPseq, ATACseq, in vitro cell cultures for hematopoietic stem cell differentiation (Dolens and Taghon, Nature Methods 2017) and retro- and lentiviral perturbation experiments for gain- and loss-of-function studies, also at the single cell level. You will work together with an international group of postdocs, PhD students and technicians in a new research building on the Ghent University Hospital campus that houses leading research groups in the field of Immunology and Genetics, thereby providing a state-of-the-art and stimulating research environment.
Profile of the candidate
Candidates should have a relevant PhD in the field of immunology, developmental biology, bioinformatics or related. You have excellent knowledge and skills in molecular biology and preferentially also in bioinformatics and RNAseq/ChIPseq data analysis. Expertise in cell culture and flow cytometry is a plus. You are highly motivated and a team player with good reporting and writing skills in English. Applicants should have a competitive publication record in peer-reviewed international journals with at least one paper as a first author.
How to apply
For further information or to apply (include motivation letter, contact details of 2-3 referees and curriculum vitae with publication list and research experience), please contact : Prof. Dr. Tom Taghon (E-mail: Tom.Taghon@UGent.be )
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