Host-pathogen: the actin cytoskeleton and bacterial toxins as research and therapeutic tools

Location
Columbus, Ohio
Salary
$48,000 per year + benefits
Posted
Jun 08, 2020
Closes
Aug 08, 2020
Contract Type
Full Time
Job Type
Postdoc

Bacterial toxins are sophisticated biological machines that are exceptionally effective in targeting weak spots in the host defense. Mechanisms behind pathogenicity of most toxins remain understood only superficially, leaving plenty of opportunities for a curious researcher to apply their skills, knowledge, and enthusiasm. A delicate ability to target essential cell elements explains the application of toxins as research and therapeutic tools. All of the above aspects of bacterial toxin pathogenicity are topics of our interest.

We are looking for outstanding, highly motivated and enthusiastic postdoctoral scientists for two projects: 1) investigate molecular and cellular mechanisms of bacterial toxins targeting the actin cytoskeleton, and 2) convert bacterial toxins into safe and potent anticancer drugs. Extensive expertise in at least one of the following areas is essential: protein expression and purification, biochemical and biophysical characterization of protein structure and function, structural biology, cell biology. Applicants with expertise in the field of the actin cytoskeleton will have priorities.

The primary responsibilities of the postdoctoral fellow will be conducting research, analyzing data, writing manuscripts. Efforts to attract funding will be welcomed and supported.

To apply, please provide: 1) a letter explaining your qualifications and interest to this position, 2) a CV or Biosketch, and 3) names and addresses of two or more professional references willing to provide letters of recommendation on your behalf.

 

Ohio State University is one of the largest colleges in the US and a vibrant community of researchers and educators. OSU is located in Columbus - the second larger city in the Midwest that offers a welcoming atmosphere, numerous cultural events, amazing restaurants. Life in Columbus is very affordable, summers are warm, springs and falls are beautiful, winters are moderately cold.

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