Research Fellow in Cancer Bioinformatics

Southampton, United Kingdom
Dec 06, 2017
Dec 11, 2017
Contract Type
Full Time

The Cancer Sciences Unit in Southampton, with over 100 scientists, clinicians and associated staff, has a long and distinguished record in the study of Cancer. 

We are now seeking a research scientist to investigate gene expression changes in various cancers; particularly within the tumour microenvironment. The candidate will work on a number of CRUK funded research programmes, predominantly as part of a team investigating the biology and immunotherapy of cancer led by Professors Mark Cragg and Jon Strefford. The successful candidate will analyse next generation sequencing (NGS)-based expression data, including ATACseq, with subsequent downstream modelling and molecular studies. The ultimate aim will be to identify and functionally characterize expression patterns determining resistance to current treatments; highlighting potential therapeutic targets.

The successful candidate will have experience of the molecular and cellular analysis of cancer-associated RNAs and/or bioinformatics and work within a dynamic, productive and friendly team of geneticists, bioinformaticians and molecular / cellular biologists based at Southampton General Hospital. This project offers the opportunity to develop a wide range of NGS, bioinformatics and molecular biology skills, and provides the prospect of collaborative work with national and international opinion-leaders in the areas of computational methods for the analysis of high-throughput RNA and ATACseq data. Your work will have important implications for the clinical management of patients, including the development of better patient stratification and the identification of novel therapeutic targets.


Interviews will be held on Monday 18 th December 2017

Informal queries should be directed to Professor Jonathan Strefford ( ).

This is a Full Time, Fixed Term post for 3 years.

Details about the Cancer Sciences Unit can be found at

The Faculty of Medicine holds an Athena SWAN Silver Award demonstrating commitment to equal opportunities and gender balance in the workplace. The Faculty recognises that applicants may seek flexible working patterns which will be considered as part of the recruitment process. For further information including key benefits designed to help maintain and support employees' well-being and work-life balance, please see our working with us website pages.


Application Procedure:

The vacancy will close at midnight on the closing date as shown above. 

References are requested along with your application. This reference system is automated so please ensure you provide the correct email address and allow time for these to be received, prior to the close date, to assist the department with shortlisting.

If you need any assistance, please call Ita Holmes (Recruitment Team) on +44 (0) 23 8059 9002. Please quote reference 934117CM on all correspondence.

We aim to be an equal opportunities employer and welcome applications from all sections of the community.

Please note that applications from agencies will not be accepted unless indicated in the job advert.