Senior Technician - Analytical Development

Location
Woburn, MA, USA
Salary
Competitive
Posted
May 18, 2018
Closes
Jun 15, 2018
Ref
1602060616
Contract Type
Full Time
Job Type
Technican
Senior Technician - Analytical Development

Req ID #: 36267

Location:

Woburn, MA, US, 01801

For nearly 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.

We are seeking an experienced Senior Technician - Analytical Development for our Biologics group located in Woburn, MA.

In this position, the Senior Technician will be responsible for developing new analytical methods and performing analytical laboratory testing according to existing methods. Experience in applying and/or developing these techniques for the analysis or process residuals, formulation development, biological product characterization or release testing, and/or biosimilar characterization will be beneficial. They will be expected to perform assay and equipment troubleshooting with minimal guidance from senior members of the group, and will be responsible for reviewing reports, raw data, other data produced by the group, and ensuring that all data packages are complete and compliant. The successful candidate will be part of a skilled analytical chemistry team, focused on the analysis of biologics in a client-driven CRO environment, working predominantly for pharmaceutical and biotech clients. The bulk of the work will be R+D, but there will be opportunities to learn and to perform to GMP compliance also.

The Senior Technician, should have experience in HPLC/UPLC and other chromatographic analyses, applied to the analysis of biologics, as well as experience in at least one of the following techniques:

+ SDS-PAGE, CE and other Gel-Electrophoretic analyses

+ ELISA / Immunoassay analyses

+ Extinction Coefficient Analysis / Amino Acid Compositional analyses

+ Glycosylation Characterization methods such as Sialic Acid or Monosaccharide analysis

The following are minimum requirements related to the Senior Technician - Analytical Development position.

+ Bachelor's degree (B.A./B.S.) or equivalent in biochemistry, chemistry, or related discipline.

+ Minimum 4 years of related industry experience in an analytical laboratory in the Pharmaceutical, Biotech or contract research laboratory (CRO) environment.

+ An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.

+ Ability to apply knowledge of analytical chemistry to complex assays. Knowledge of basic protein /peptide analytical techniques and demonstrated ability to operate typical laboratory equipment, specifically HPLC, Plate Reader, CE, spectrophotometer and other laboratory equipment required. Computer proficiency in MS Word, Excel, Outlook, instrumentation and analysis software. Excellent verbal, written communication and organizational skills. Demonstrated independent analytical and problem solving abilities. Demonstrated knowledge of GMP regulations. Must possess excellent interpersonal skills to maintain communication across functional groups, and must be able to communicate effectively in a small group or one on one setting.

About Biologics Testing SolutionsWith more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Offering a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs. Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team.

About Charles RiverCharles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 11,000 employees within 70 facilities in 18 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2016, revenue increased by 23.3% to $1.68 billion from $1.36 billion in 2015. At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~70% of the drugs approved by the FDA in 2016

For more information, please visitwww.criver.com.

Equal Employment OpportunityCharles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet