Research Technician I, ADME/DMPK 1
For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work e perform. In return, we'll help you build a career that you can feel passionate about.
We are seeking an experienced Research Technician in ADME for our Safety Assessment site located in Ashland, OH. Responsible for the performance of assigned animal studies in accordance with Good Laboratory Practice Regulations and Standard Operating Procedures with little supervision/instruction. Responsibilities include animal husbandry, dosing and observation of live animals, sample collection and analysis, necropsy, preparation of common laboratory solutions, safe handling of various radioactive isotopes, and the maintenance and review of study records.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
- Perform in-life technical procedures (e.g., clipping, handling, binding, removals, body weight, dosing).
- Administer test substances by various basic methods (e.g., oral gavage).
- Input, print and edit computer entries (e.g., in life numbers, body weights, food consumption and clinical observation).
- Under supervision may act as lead/primary technician on basic studies.
- Observe animals for general health and overall well being.
- Collect and record research data and biological specimens in compliance with Good Laboratory Practice Regulations (GLPs), study protocols and Standard Operating Procedures (SOPs).
- Read basic study protocols and extract pertinent information.
- Review documentation of functions performed as part of quality control requirements.
- Retrieve and view SOPs using appropriate database.
- Use GLPs, SOPs, processes and company policies when performing all job functions.
- Handle, restrain, and provide care for all species of laboratory animals at the site.
- Perform study preparation activities including collection tube labeling and room setup.
- Maintain clean work areas (e.g.: laboratory area, primary enclosures, animal exam areas).
- Receive animals (e.g., general health observation, sexing and identification) of all species, if applicable for the site.
- Perform all other related duties as assigned.
- Education: High school diploma or General Equivalent Degree (G.E.D.). Bachelor's preferred (B.S) or equivalent in animal or life science or related discipline.
- Experience: 6 months to 1 year related experience in animal research and/or husbandry or must have fully satisfied technical and experience requirements for the previous level.
- An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
- Certification/Licensure: ALAT preferred
Other: Ability to handle common laboratory species. Proficient in basic technical skills and the operation of data collection equipment. Knowledge of GLPs and other federal regulations and guidelines relating to the care of laboratory animals. Basic understanding of study design and protocols.
About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.
About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 11,000 employees within 70 facilities in 18 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2016, revenue increased by 23.3% to $1.68 billion from $1.36 billion in 2015.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~70% of the drugs approved by the FDA in 2016.
For more information, please visit www.criver.com .
Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet