Research Technician - Immunology and Immunotherapy - 56362 - Band 500

Location
Birmingham
Salary
Competitive
Posted
Jul 10, 2019
Closes
Aug 10, 2019
Ref
190000DJ
Contract Type
Full Time
Job Type
Technican
Position Details

Department: Institute of Immunology and Immunotherapy

Location- University of Birmingham, Edgbaston, Birmingham, UK

Full time starting salary is normally in the range £22,722 to £24,411. With potential progression once in post to £28,259 a year

Band 500

Full time, fixed term until 31st December 2019

Job Purpose

We have funding to support a research technician SB500 through an MRC project grant MR/P001874/1, "Determining the potential universal applicability of a diurnal response to vaccination and the associated circadian immune processes" The technician will support the project by being involved in animal experiments and laboratory analyses, analysing immune cell activation using flow cytometry, real time PCR, fluorescence microscopy and ELISA.

Main duties

Research - 75%

The candidate will support a MRC project grant to Janet Lord and Kai-Michael Toellner on the regulation of diurnal variation of the vaccine response in mice. He/she will work directly with KMT and embedded in his lab group in the UoB Medical School Institute of Biomedical Research.

The candidate will analyse B cell responses to vaccination in mice. He/she will

• Prepare antigens to immunize mice

• Dissect animals and sample tissues and blood

• Analyse antibody titres using ELISA

• Analyse the cellular immune response using immunohistology and fluorescence

microscopy, prepare stained cell suspensions for flow cytometry and sorting, and analyse

gene expression using real time PCR.

• Experimental data will be recorded and analysed.

The technician will already be proficient in these techniques, or will be able to use and apply these techniques independently after being trained by experienced members of the lab.

This knowledge is to be gained from extensive practical experience and formal qualifications.

The technical and/or other skills will vary according to the work area and support the requirements of research group(s) working within the area. However it is expected that all appropriate/required knowledge/skill base will be delivered at the "higher level" and include but are not restricted/limited to the following

• Safe working practices

• Working to deadlines and providing consistent results delivery

• Resolving problems that may affect the achievement of objectives and deadlines

• Communicating results to colleagues

• Providing support and guidance to junior members of staff and/or students

• Maintaining good record keeping

• An awareness of University & Trust Health & Safety policies and procedures (if applicable)

HEALTH AND SAFETY/ENVIRONMENTAL ISSUES - 10%

• Enabling staff and students, working within the area of responsibility, to comply with all

basic University / College Health & Safety policies This will include compliance by all staff

with current rules governing work with COSHH, genetically modified organisms (GMOs),

biological samples, human tissue, radioactive materials and schedule 5 toxins etc. Ensure

all required assessments are in place approved and up to date.

• Maintaining records both paper and computer based as appropriate.

• Carrying out regular maintenance processes such as flushing eye wash stations as

appropriate and ensuring records are maintained.

• Reporting any breaches or non-compliance with H&S procedures to the PI, Technical

Manager, Laboratory Manager or College Safety Adviser.

• Upholding the correct waste disposal stream as governed by College and local policy for

laboratory, recycled and general waste

• Adopt a proactive attitude to assisting with and implementing carbon reduction and energy

saving measures

GENERAL ADMINISTRATION AND ORGANISATION - 8%

The post holder will assist with the daily administration and organisation of the work area.

These duties include:

• Maintaining stocks of consumables, if necessary, creating purchase order requisitions for

the College finance office or via web based ordering system

• Receipt and correct storage of consumables and chemical reagents.

• Ensuring that the facilities are maintained in a clean, functional and safe condition,

reporting any problems through the appropriate channels.

• Ensuring the best use of equipment through booking systems, if appropriate

• Reporting any problems with equipment or services to the line manager as appropriate.

• Any other duties commensurate with the grade and skill base of the post holder as directed

by either the Principle investigator for research based activities or the Technical Managers

for non-research based activities

OTHER DUTIES - 7%

• In collaboration with the Laboratory Manager or supervisor the post holder will take an active role in the training and mentoring process for junior or newly appointed staff/students

• To actively engage in the Personal Development Process

• To contribute at a level appropriate with the grade, to internal and external audit procedures, and to regulatory inspections.

• Assist Technical Managers and/or Laboratory Managers in identifying and tracking items held on the University asset register.

Dimensions

This post provides technical support to a research group comprising of:

1. Professor(s) 1

2. Research Fellows 2

3. Technician(s) 1

4. Postgraduate Students 3

• The post has no direct line management responsibility for other staff

• The post has no budgetary or financial responsibility

• The impact of this role is to enhance the University's research power and to provide students (BMedSc/MRes/PhD) with a distinctive high quality experience

Planning and organising

• The work will come to the role holder via regular meetings with either the research group, PI or nominated Research Fellow

• The role holder will set their own deadline priorities within the deadlines provided by the PI for dealing with the work provided

• The role is forward planning to meet research milestones but there is some element of reactiveness and problem solving should obstacles arise.

• The role holder will use the most appropriate technique and ensure that all the equipment and consumables are available to ensure results delivery

• The role holder will plan with other stakeholders the most efficient use of resources and equipment to reach research milestones

Problem Solving and Decision-making without reference to others

• Deliver a level of service to colleagues/customers as outlined in work plans/PDR objectives

• Perform day to day research experiments with approved protocols, collate and analyse data as appropriate

• Use own judgement based on experience to break down and assess problems and implement changes within area of expertise

• Responsible for ensuring compliance of housekeeping policies within the defined area and taking any necessary remedial action

• Routine operation and maintenance of laboratory equipment

• Replace consumables and reagents

After consulting others

• Change in direction of research or service activities to be discussed with line manager or

academic supervisors

• Procurement of equipment or arranging equipment repair or servicing to be discussed with

line manager

• Preparation/delivery of presentations to internal/external audiences

or would be referred to someone else

• Set long term priorities

• Make decisions on major purchases

• Any issues outside the area of expertise of the post holder. Any issues which may have a

detrimental impact on the core business activities of the College and/or University

Person Specification

• Degree or equivalent professional qualification in an appropriate subject
• GCSE (A*- C) or equivalent in mathematics
• In-depth practical knowledge of technical and scientific methods stated above and Good Laboratory Practice gained through extensive experience and formal qualification
• Extensive experience of similar laboratory based work
• Positive service attitude and shows courtesy in dealing with others
• Ability to organise and manage own work load and demonstrate flexibility in terms of work practices/requirements
• Ability to work under minimal supervision but function as part of a team
• Knowledge of current relevant H&S policies
• Proficiency in commonly used software packages

Planning and organising

• The work will come to the role holder via regular meetings with either the research group, PI or nominated Research Fellow

• The role holder will set their own deadline priorities within the deadlines provided by the PI for dealing with the work provided

• The role is forward planning to meet research milestones but there is some element of reactiveness and problem solving should obstacles arise.

• The role holder will use the most appropriate technique and ensure that all the equipment and consumables are available to ensure results delivery

• The role holder will plan with other stakeholders the most efficient use of resources and equipment to reach research milestones

Problem Solving and Decision-making

Without reference to others

• Deliver a level of service to colleagues/customers as outlined in work plans/PDR objectives

• Perform day to day research experiments with approved protocols, collate and analyse data as appropriate

• Use own judgement based on experience to break down and assess problems and implement changes within area of expertise

• Responsible for ensuring compliance of housekeeping policies within the defined area and taking any necessary remedial action

• Routine operation and maintenance of laboratory equipment

• Replace consumables and reagents

After consulting others

• Change in direction of research or service activities to be discussed with line manager or academic supervisors

• Procurement of equipment or arranging equipment repair or servicing to be discussed with line manager

• Preparation/delivery of presentations to internal/external audiences

or would be referred to someone else

• Set long term priorities

• Make decisions on major purchases

• Any issues outside the area of expertise of the post holder. Any issues which may have a detrimental impact on the core business activities of the College and/or University

Further particulars can be found here: http://www.download.bham.ac.uk/vacancies/jd/MDSFPs.pdf

For further information please contact Dr K Toellner k.m.toellner@bham.ac.uk