Imaging Genomics

Abstract

Imaging genomics studies the relationship of clinical imaging features with genomic/molecular characteristics and has great potential to improve the diagnosis, treatment planning, and monitoring of patients with glioblastoma (GBM). While still a relatively young field, imaging genomics has made significant progress over the past decade. Here, we review clinically relevant genomic and molecular features of GBM, briefly describe MRI techniques with utility in the evaluation of GBM, and provide an overview of imaging genomics applications in the development of biomarkers of molecular tumor characteristics. Lastly we discuss how this approach can be leveraged to improve characterization of entire tumors throughout a patient’s treatment course in a non-invasive manner.