Background: Lipoprotein lipase regulates fat uptake into adipose tissue. Results: A mouse model with increased adipose tissue lipoprotein lipase has improved glucose metabolism when challenged with a high fat diet. Conclusion: Increasing adipose tissue lipoprotein lipase improves adipose tissue function. Significance: Adipose tissue lipoprotein lipase protects against obesity-induced glucose and insulin intolerance.
CITATION STYLE
Walton, R. G., Zhu, B., Unal, R., Spencer, M., Sunkara, M., Morris, A. J., … Finlin, B. S. (2015). Increasing adipocyte lipoprotein lipase improves glucose metabolism in high fat diet-induced obesity. Journal of Biological Chemistry, 290(18), 11547–11556. https://doi.org/10.1074/jbc.M114.628487
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