Skip to content

Making digit patterns in the vertebrate limb

by Cheryll Tickle
Nature Reviews Molecular Cell Biology ()
Get full text at journal


The vertebrate limb has been a premier model for studying pattern formation — a striking digit pattern is formed in human hands, with a thumb forming at one edge and a little finger at the other. Classic embryological studies in different model organisms combined with new sophisticated techniques that integrate gene-expression patterns and cell behaviour have begun to shed light on the mechanisms that control digit patterning, and stimulate re-evaluation of the current models.

Cite this document (BETA)

Readership Statistics

156 Readers on Mendeley
by Discipline
81% Agricultural and Biological Sciences
7% Medicine and Dentistry
5% Biochemistry, Genetics and Molecular Biology
by Academic Status
28% Student > Ph. D. Student
25% Researcher
12% Student > Bachelor
by Country
4% United States
3% United Kingdom
2% Germany

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Sign up & Download

Already have an account? Sign in