Skip to content

Only connect: Personal genomics and the future of american medicine

by Misha Angrist
Molecular Diagnosis and Therapy ()
Get full text at journal


Access to one's own complete genome was unheard of just a few years ago. At present we have a smattering of identifiable complete human genomes, but the coming months and years will undoubtedly bring thousands more. What will this mean for the practice of medicine in the US? No one knows, but given the remarkable drop in the cost of DNA sequencing over the last few years, it seems a safe bet that within the next decade, primary care physicians will order patients' whole genome sequences with no more fanfare than they would a complete blood count. But the challenges of transforming that easily accessible information into cost savings and better health outcomes will be daunting. Obviously, we lack interpretive abilities and phenotypic information commensurate with our skill in amassing DNA sequences. Worse, we have exacerbated these problems by failing to embrace the increasing ubiquity of genomic information, the populace's interest in it, and its relevance to virtually every medical specialty. The success of personal genomics will require a profound cultural shift by every entity with a stake in human health.

Author-supplied keywords

Cite this document (BETA)

Readership Statistics

15 Readers on Mendeley
by Discipline
33% Medicine and Dentistry
27% Agricultural and Biological Sciences
20% Social Sciences
by Academic Status
27% Student > Ph. D. Student
20% Other
20% Researcher
by Country
13% Canada
7% United States

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Sign up & Download

Already have an account? Sign in