Oxidative photoredox catalysis: Mild and selective deprotection of PMB ethers mediated by visible light

Abstract

Herein we report an advancement in the application of visible light photoredox catalysts in the oxidation of electron-rich arenes resulting in the selective deprotection of para-methoxybenzyl (PMB) ethers. This method is highlighted by excellent functional group tolerance, protecting group orthogonality, mild reaction conditions and avoidance of stoichiometric redox byproducts. © 2011 The Royal Society of Chemistry.