We show that there is a physical analogy between a stochastic model of a genetic toggle switch system and a thermostated particle moving in a potential field, derived from the probability distribution of the toggle switch. This result suggests that one can actually simulate the dynamics of a more complex gene network by considering an ensemble of thermostated particles moving in a potential field, derived from the stationary distribution of the chemical stochastic model describing the gene network. © Mary Ann Liebert, Inc.
CITATION STYLE
Andrecut, M., & Kauffman, S. A. (2007). A physical analogy of the genetic toggle switch. Journal of Computational Biology, 14(7), 973–983. https://doi.org/10.1089/cmb.2007.0038
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