Repopulation of cancer cells during therapy: an important cause of treatment failure.

by J. Kim, I. Tannock
Nature reviews. Cancer ()


Radiotherapy and chemotherapy are given in multiple doses, which are spaced out to allow the recovery of normal tissues between treatments. However, surviving cancer cells also proliferate during the intervals between treatments and this process of repopulation is an important cause of treatment failure. Strategies developed to overcome repopulation have improved clinical outcomes, and now new strategies to inhibit repopulation are emerging in parallel with advances in the understanding of underlying biological mechanisms.

Cite this document (BETA)

Readership Statistics

120 Readers on Mendeley
by Discipline
by Academic Status
18% Ph.D. Student
15% Researcher (at a non-Academic Institution)
13% Post Doc
by Country
6% United States
2% Germany
2% Canada

Sign up today - FREE

Mendeley saves you time finding and organizing research. Learn more

  • All your research in one place
  • Add and import papers easily
  • Access it anywhere, anytime

Start using Mendeley in seconds!

Sign up & Download

Already have an account? Sign in